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Phospholine Iodide (echothiophate iodide) is an ophthalmic cholinesterase inhibitor used to treat glaucoma and certain eye muscle disorders. It works by increasing acetylcholine levels in the eye, causing pupil constriction and reduced intraocular pressure. This medication is typically reserved for patients who haven't responded well to other glaucoma treatments.
Phospholine Iodide is an eye drop medication used to lower eye pressure in glaucoma patients and treat certain eye muscle disorders.
Key facts at a glance
- RxNorm
- 204232
- Generic
- Phospholine Iodide
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Chronic open-angle glaucoma, secondary glaucoma, and strabismus (crossed eyes) in both adults and children. May also be used for certain diagnostic procedures.
As a cholinesterase inhibitor, it prevents the breakdown of acetylcholine, leading to increased cholinergic activity. This causes pupil constriction (miosis) and improved outflow of aqueous humor, reducing intraocular pressure.
May cause blurred vision and brow ache, especially initially. Can interact with other medications including certain anesthetics. Requires refrigeration storage. Long-term use may increase risk of cataracts and retinal detachment. Pregnant women should use with caution.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy