Pipothiazine
Pipothiazine is a typical antipsychotic medication belonging to the phenothiazine class, primarily used to manage symptoms of schizophrenia and other psychotic disorders. It works by blocking dopamine receptors in the brain, helping to reduce hallucinations, delusions, and disorganized thinking. This medication may also be used for severe behavioral disturbances.
A first-generation antipsychotic used to treat schizophrenia and psychotic symptoms by reducing dopamine activity in the brain.
Key facts at a glance
- ATC
- N05AC04
- RxNorm
- 8348
- Generic
- Pipothiazine
- Class
- atc-n05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of schizophrenia and related psychotic disorders, including management of positive symptoms such as hallucinations and delusions. May also be prescribed for severe anxiety disorders and behavioral disturbances when other treatments have been ineffective.
Pipothiazine exerts its effects primarily by blocking dopamine D2 receptors in the brain's mesolimbic pathway, which helps reduce psychotic symptoms. It also has anticholinergic and antihistaminic properties that contribute to its sedative effects.
May cause side effects including sedation, extrapyramidal symptoms (movement disorders), orthostatic hypotension, and anticholinergic effects. Requires careful monitoring in elderly patients with dementia-related psychosis. Should not be stopped abruptly without medical consultation. May interact with other CNS depressants and medications affecting heart rhythm.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy