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Sodium Chloride, Sodium Acetate, Potassium Chloride, Magnesium Chloride

Published: July 26, 2026Updated: July 26, 2026

Plasma-Lyte 148 is a balanced crystalloid intravenous solution containing multiple electrolytes including sodium, potassium, magnesium, chloride, acetate, and gluconate. It is used for fluid resuscitation, maintenance of hydration, and electrolyte replacement in patients who are unable to receive adequate fluids and electrolytes orally. This medication is commonly administered in hospital settings including surgical procedures, trauma care, and critical care units.

Quick summary

Plasma-Lyte 148 is an IV electrolyte solution used to hydrate patients and restore essential minerals when oral intake is not possible.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
33829
Generic
Plasma-Lyte 148
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for fluid and electrolyte replacement in patients requiring IV hydration, including those recovering from surgery, experiencing dehydration, or unable to take fluids by mouth. Also used during surgical procedures and in critical care settings for volume resuscitation and maintenance of intravascular volume.

Provides isotonic fluid that distributes throughout the extracellular compartment, helping to restore and maintain normal fluid balance and electrolyte levels. The balanced electrolyte composition mimics the composition of plasma more closely than traditional saline-based solutions.

Should be administered intravenously by healthcare professionals in appropriate clinical settings. Use with caution in patients with heart failure, kidney impairment, or conditions affecting fluid balance. Monitor electrolyte levels during prolonged use. Not for subcutaneous or intramuscular administration.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy