Podofilox
Podofilox is a topical medication used to treat visible external genital and anal warts (condyloma acuminata). It works by causing cell death (necrosis) of the wart tissue when applied directly to the affected areas. This prescription medication is intended for patient self-administration under medical guidance.
Podofilox is a topical treatment for external genital and anal warts that destroys wart tissue through local application.
Key facts at a glance
- ATC
- D06BB04
- RxNorm
- 8463
- Generic
- Podofilox
- Class
- atc-d06
- Brands
- Condylox
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- gel, solution, cream
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of visible, external genital and anal warts (condyloma acuminata) caused by human papillomavirus (HPV). It is approved for use in adults and is applied directly to the wart tissue by the patient.
Podofilox is a cytotoxic agent that, when applied topically to genital warts, causes necrosis (cell death) of the visible wart tissue. The exact molecular mechanism of action is not fully understood, but it disrupts cell division and leads to destruction of the treated wart tissue.
Podofilox is for external use only and should not be applied to internal warts or mucous membranes. Common side effects include local irritation, burning, pain, and inflammation at the application site. Treatment should be discontinued if severe skin reactions occur. It is contraindicated in pregnancy and should not be used on open wounds or bleeding warts. Patients should wash hands thoroughly after application and avoid sexual contact immediately after use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy