Polymyxin B, Dexamethasone
Poly-Dex is a brand-name ophthalmic medication combining an antibiotic (polymyxin B) with a corticosteroid (dexamethasone). It is prescribed for eye infections accompanied by inflammation, particularly bacterial conjunctivitis and blepharoconjunctivitis. The combination allows treatment of bacterial infection while reducing associated swelling and discomfort.
Poly-Dex is an eye medication combining an antibiotic and anti-inflammatory agent for treating bacterial eye infections with associated inflammation.
Key facts at a glance
- RxNorm
- 219289
- Generic
- Poly-Dex
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Poly-Dex is used to treat bacterial eye infections with significant inflammation, including blepharoconjunctivitis, bacterial conjunctivitis, and eye conditions following corneal injuries where infection and inflammation coexist.
Polymyxin B is an antibiotic that works by disrupting bacterial cell membranes, particularly effective against gram-negative bacteria. Dexamethasone is a corticosteroid that reduces inflammation, redness, and swelling by suppressing the local immune response.
Poly-Dex is for ophthalmic use only and should not be injected. Do not use if you have viral or fungal eye infections, untreated herpes simplex, or certain other eye conditions. Side effects may include temporary blurred vision, eye irritation, or delayed wound healing. Use exactly as prescribed and complete the full course even if symptoms improve.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy