Polythiazide
Polythiazide is a thiazide diuretic used to treat high blood pressure and fluid retention (edema). It works by helping the kidneys remove excess salt and water from the body, which reduces the workload on the heart and lowers blood pressure.
Polythiazide is a thiazide diuretic that helps lower blood pressure and reduce fluid retention by increasing urine output.
Key facts at a glance
- ATC
- C03AA05
- RxNorm
- 8565
- Generic
- Polythiazide
- Class
- atc-c03
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Polythiazide is primarily used to treat hypertension (high blood pressure) and edema associated with conditions such as heart failure, liver cirrhosis, and kidney disorders.
As a thiazide diuretic, polythiazide inhibits sodium reabsorption in the distal convoluted tubules of the kidney, promoting the excretion of sodium, water, and electrolytes through increased urine production.
Common side effects include electrolyte imbalances (especially low potassium), increased urination, dizziness, and sensitivity to sunlight. Regular blood tests may be needed to monitor electrolyte levels and kidney function. Patients should inform their doctor of any allergies to sulfonamide-derived medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy