Pomalidomide
Pomalyst (pomalidomide) is a prescription medication used to treat multiple myeloma, a cancer of plasma cells. It belongs to a class of drugs called immunomodulatory agents and is typically given to patients who have already received at least two prior treatments including lenalidomide and a proteasome inhibitor.
Pomalyst is an immunomodulatory drug used to treat multiple myeloma in patients who have failed prior therapies.
Key facts at a glance
- RxNorm
- 1369719
- Generic
- Pomalyst
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of multiple myeloma in adult patients who have received at least two prior therapies including lenalidomide and a proteasome inhibitor (such as bortezomib or carfilzomib).
Pomalidomide is an immunomodulatory and antiangiogenic agent. It works by inhibiting the growth and spread of cancer cells, modulating the immune system through effects on T-cells and natural killer cells, and reducing blood vessel formation to tumors.
This medication carries a boxed warning for embryo-fetal toxicity and thromboembolic risks. Patients must enroll in a restricted distribution program and use effective contraception. Common side effects include fatigue, neutropenia, anemia, and thrombocytopenia. Regular blood monitoring is required during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy