Orbifloxacin, Mometasone, and Posaconazole
Posatex is a prescription veterinary otic suspension for dogs that treats ear infections (otitis externa). It combines three active ingredients—an antibiotic, an antifungal, and an anti-inflammatory agent—to address infections caused by bacteria, yeast, and fungi while reducing associated inflammation and discomfort.
A prescription ear medication for dogs that treats ear infections using a combination antibiotic, antifungal, and anti-inflammatory formulation.
Key facts at a glance
- RxNorm
- 2105738
- Generic
- Posatex
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Posatex is used to treat otitis externa (outer ear infections) in dogs caused by susceptible strains of bacteria and yeast/fungi. It is typically prescribed when an infection involves multiple types of organisms or when inflammation is significant.
This medication contains three active ingredients: orbifloxacin (a fluoroquinolone antibiotic that kills susceptible bacteria), posaconazole (an antifungal that inhibits fungal cell membrane formation), and mometasone (a corticosteroid that reduces inflammation, itching, and swelling in the ear canal).
Posatex is for veterinary use only and requires a prescription from a veterinarian. It is intended for use in dogs and should not be used in cats or other animals unless specifically directed. The medication is applied topically to the ear canal. As with all medications, some patients may experience local reactions. Always follow your veterinarian's instructions regarding dosing and duration of treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy