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Potassium Bitartrate

Published: July 26, 2026Updated: July 26, 2026

Potassium Bitartrate (PHEXX) is a vaginal medication that creates an acidic environment to reduce sperm motility. It works by maintaining a vaginal pH between 3.5 and 4.5, which is hostile to sperm survival. This product is designed for use as a non-hormonal contraceptive option.

Quick summary

A vaginal contraceptive that creates an acidic environment to prevent pregnancy by reducing sperm motility.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
223779
Generic
Potassium Bitartrate
Class
unclassified
Brands
Phexxi, Phexx, Ceo-Two
Availability
rx
Lactation
unknown
Routes
vaginal, rectal
Forms
gel
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used as a non-hormonal vaginal contraceptive for pregnancy prevention, applied post-coitally.

The medication produces an acidic vaginal pH range of 3.5-4.5, which inhibits sperm motility and creates a hostile environment for sperm survival. Clinical studies showed pH levels below 5 in most subjects after use.

For vaginal use only. Should be applied after intercourse. Patients should follow specific application instructions provided by their healthcare provider. Not suitable for all patients; consult with a healthcare professional regarding appropriateness and potential interactions with other vaginal products.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy