Mogamulizumab
Poteligeo (mogamulizumab) is a prescription monoclonal antibody medication used to treat certain types of non-Hodgkin lymphoma, specifically relapsed or refractory mycosis fungoides and Sézary syndrome in adults who have received at least one prior systemic therapy. It works by targeting and binding to a specific protein on cancer cells called CCR4, helping the immune system recognize and eliminate these malignant cells.
Poteligeo is an IV monoclonal antibody treatment for certain types of cutaneous T-cell lymphoma that works by targeting CCR4 proteins on cancer cells.
Key facts at a glance
- RxNorm
- 2054082
- Generic
- Poteligeo
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of adult patients with relapsed or refractory mycosis fungoides (MF) or Sézary syndrome (SS) after at least one prior systemic therapy. This medication is specifically indicated for cutaneous T-cell lymphoma (CTCL).
Poteligeo is a monoclonal antibody that binds to the C-C chemokine receptor type 4 (CCR4), which is expressed on the surface of certain malignant T-cells in mycosis fungoides and Sézary syndrome. By binding to CCR4, it enables the immune system to recognize and destroy the cancer cells.
Administered as an intravenous infusion. Common side effects include infusion reactions, skin reactions, fatigue, diarrhea, and upper respiratory infections. May increase risk of infections and autoimmune complications. Requires close monitoring during and after treatment. Should be administered by healthcare professionals experienced in cancer treatment.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy