Alirocumab
Praluent (alirocumab) is a prescription medication used to treat adults with heterozygous familial hypercholesterolemia (an inherited condition causing high cholesterol) or clinical atherosclerotic cardiovascular disease who need additional cholesterol lowering. It is a PCSK9 inhibitor administered as a subcutaneous injection, typically used alongside statin therapy and diet.
Praluent is an injectable PCSK9 inhibitor used to lower LDL cholesterol in patients with certain types of high cholesterol or heart disease.
Key facts at a glance
- RxNorm
- 1659157
- Generic
- Praluent
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats heterozygous familial hypercholesterolemia and reduces cardiovascular risk in patients with clinical atherosclerotic cardiovascular disease who require additional LDL cholesterol lowering beyond statin therapy alone.
Praluent is a monoclonal antibody that binds to and inhibits the PCSK9 protein, allowing the liver to remove more LDL cholesterol from the bloodstream by increasing LDL receptor availability.
Administered as a subcutaneous injection (typically every 2 weeks). Common side effects may include injection site reactions, flu-like symptoms, and itching. Should be used as adjunct to diet and statin therapy. Patients should be monitored for allergic reactions. Not recommended during pregnancy unless clearly needed.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy