Pramlintide
Pramlintide is an injectable amylin analog used as an additional treatment for diabetes mellitus, working by mimicking the hormone amylin to help regulate blood glucose levels.
Pramlintide is an amylin analog injectable used alongside insulin to improve blood sugar control in diabetic patients.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- A10BX05
- RxNorm
- 139953
- Generic
- Pramlintide
- Class
- atc-a10
- Brands
- Symlin
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Adjunctive treatment for type 1 and type 2 diabetes mellitus in adults who use mealtime insulin and have not achieved adequate glycemic control. It is not a substitute for insulin.
Pramlintide mimics human amylin, a peptide hormone that complements insulin by suppressing postprandial glucagon secretion, slowing gastric emptying, and promoting satiety. These combined actions help reduce blood sugar spikes after meals.
Must be administered separately from insulin (cannot be mixed) with appropriate dosing adjustments. Common side effects include nausea and hypoglycemia, particularly when combined with insulin. Not recommended for patients with gastroparesis or hypoglycemia unawareness.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy