Pergolide
Prascend is a dopamine agonist medication primarily used in veterinary medicine to manage pituitary pars intermedia dysfunction (PPID), commonly known as equine Cushing's disease, in horses. The active ingredient, pergolide, helps control the overproduction of hormones by stimulating dopamine receptors in the brain. This medication is available only by prescription and requires careful monitoring during treatment.
Prascend is a prescription medication for horses with Cushing's disease that helps regulate hormone overproduction through dopamine agonist activity.
Key facts at a glance
- RxNorm
- 1191349
- Generic
- Prascend
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prascend is indicated for the control of clinical signs associated with pituitary pars intermedia dysfunction (PPID) in horses, a condition that causes hormonal imbalances leading to symptoms such as abnormal hair coat, laminitis, muscle wasting, and excessive thirst.
As a dopamine agonist, Prascend stimulates dopamine receptors in the brain, which helps suppress the overactive pituitary gland in affected horses. This reduces the excessive production of adrenocorticotropic hormone (ACTH) and other hormones that cause the clinical signs of PPID.
Prascend is for oral use in horses only and should not be handled by individuals who are pregnant or trying to conceive. Horses on Prascend should be monitored regularly, including periodic ACTH testing. Possible side effects may include loss of appetite, diarrhea, or lethargy. The medication should be stored at room temperature and used as directed by a veterinarian.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy