Praziquantel
Praziquantel is an anthelmintic medication used to treat infections caused by parasitic worms, including schistosomiasis (bilharzia), liver flukes, and tapeworms. It works by paralyzing and killing susceptible parasites, allowing the body to eliminate them naturally. This oral medication is commonly prescribed for both acute and chronic parasitic infections, particularly in endemic regions.
Praziquantel is an anti-parasitic medication used to treat various worm infections including schistosomiasis, tapeworms, and liver flukes.
Key facts at a glance
- ATC
- P02BA01
- RxNorm
- 8628
- Generic
- Praziquantel
- Class
- atc-p02
- Brands
- Sentinel Spectrum, Quest Plus, Virbantel, Biltricide, Droncit, Interceptor Plus, Iverhart, NexGard Combo, Giarcidia, Prazimectin, Profender, Drontal Plus, Drontal, Equimax, Triple Wormer
- Availability
- rx
- Lactation
- unknown
- Routes
- topical, oral
- Forms
- solution, tablet, gel, suspension
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Praziquantel is used to treat schistosomiasis (bilharzia) caused by Schistosoma species, as well as infections from liver flukes (Clonorchis sinensis, Opisthorchis species) and intestinal tapeworms (Taenia species, Diphyllobothrium latum). It is also effective against neurocysticercosis in combination with other therapies.
Praziquantel causes rapid contraction of parasites by affecting their calcium channels, leading to paralysis and detachment from host tissues. The drug also damages the parasite's tegument, making it vulnerable to the host's immune system.
Praziquantel is generally well-tolerated but may cause dizziness, headache, or abdominal discomfort. It should be taken with food and not crushed or chewed due to its bitter taste. Patients with ocular cysticercosis should avoid treatment as drug-induced inflammation can damage the eye. A second dose 2-6 weeks after initial treatment may be needed for complete cure.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy