Prelief
Prelief is a brand-name calcium glycerophosphate supplement designed to help reduce discomfort from acidic foods and beverages. It is marketed for individuals who experience digestive upset, heartburn, or urinary irritation when consuming acidic items such as coffee, tomato-based foods, or citrus fruits.
Prelief is an over-the-counter supplement containing calcium glycerophosphate that helps neutralize dietary acid to reduce heartburn, digestive discomfort, and urinary irritation associated with acidic foods.
Key facts at a glance
- RxNorm
- 723742
- Generic
- Prelief
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prelief is used to help manage discomfort associated with acidic foods and beverages, including heartburn, acid reflux symptoms, and urinary irritation or sensitivity caused by acidic foods like coffee, citrus, tomatoes, and wine. It is often used by individuals seeking to reduce digestive upset without antacids.
Prelief contains calcium glycerophosphate, which acts as an acid buffer. When taken with acidic foods or beverages, it helps neutralize excess acid, potentially reducing the irritant effects on the stomach, esophagus, and urinary tract.
Prelief is sold as a dietary supplement rather than an FDA-approved medication, so it has not undergone the same rigorous testing for safety and efficacy. Users should consult a healthcare provider before use, especially those with kidney conditions, on calcium-restricted diets, or taking other medications. It is not intended to treat diagnosed medical conditions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy