Darunavir and Cobicistat
Prezcobix is a combination antiretroviral medication containing darunavir and cobicistat, used to treat HIV-1 infection in adults and children. It works by inhibiting the HIV protease enzyme and boosting drug levels in the body.
Prezcobix is an HIV protease inhibitor combination used as part of antiretroviral therapy for HIV-1 infection.
Key facts at a glance
- RxNorm
- 1600705
- Generic
- Prezcobix
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prezcobix is indicated for the treatment of HIV-1 infection in adults and pediatric patients, used in combination with other antiretroviral agents.
Prezcobix contains darunavir, a protease inhibitor that blocks HIV replication by inhibiting the protease enzyme, and cobicistat, which acts as a pharmacokinetic enhancer by inhibiting CYP3A enzymes to increase darunavir blood levels.
Prezcobix does not cure HIV/AIDS and must be used with other antiretroviral drugs. Resistance testing is recommended before initiation. Patients should be monitored for kidney function and drug interactions. It is not recommended for patients with severe hepatic impairment. Common side effects may include nausea, diarrhea, and rash.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy