Omeprazole
Prilosec (omeprazole) is a proton pump inhibitor that reduces stomach acid production. It is used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and erosive esophagitis. Available in both prescription and over-the-counter formulations.
Prilosec is an acid-reducing medication used to treat conditions caused by excess stomach acid.
Key facts at a glance
- RxNorm
- 203345
- Generic
- Prilosec
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prilosec is prescribed for the treatment of GERD, active duodenal and gastric ulcers, erosive esophagitis, and is used in combination with antibiotics for H. pylori eradication. The OTC version is approved for frequent heartburn relief.
Prilosec works by irreversibly blocking the hydrogen-potassium ATPase pump in gastric parietal cells, which is responsible for acid secretion into the stomach lumen. This reduces the amount of acid produced.
Prilosec may increase the risk of bone fractures with long-term use and may affect absorption of certain medications like clopidogrel and iron supplements. It should be used at the lowest effective dose for the shortest duration appropriate. Users should consult their healthcare provider before starting therapy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy