Ephedrine and Guaifenesin
Primatene With Ephedrine & Guaifenesin is an over-the-counter bronchodilator combined with an expectorant. It is designed for temporary relief of mild asthma symptoms such as wheezing, shortness of breath, and chest congestion.
An OTC combination medication for temporary relief of asthma symptoms including airway constriction and mucus buildup.
Key facts at a glance
- RxNorm
- 2591378
- Generic
- Primatene With Ephedrine & Guaifenesin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves wheezing, chest tightness, shortness of breath, and congestion associated with mild asthma. May also be used for bronchial asthma and other conditions causing bronchoconstriction.
Ephedrine acts as a bronchodilator to help relax and open airways, while guaifenesin works as an expectorant to help thin and loosen mucus in the airways, making it easier to clear.
For occasional use only; not a substitute for prescription asthma medications. Consult a healthcare provider before use if you have heart conditions, high blood pressure, thyroid disease, or diabetes. Do not exceed recommended doses. Seek medical attention if symptoms worsen or do not improve.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy