Factor IX Complex
Profilnine is a brand-name Factor IX complex medication used to treat and prevent bleeding in patients with hemophilia B (Christmas disease), a genetic disorder characterized by deficiency of clotting Factor IX. It is also used for rapid reversal of warfarin anticoagulation when bleeding occurs or surgery is needed.
Profilnine is a clotting factor replacement therapy for hemophilia B patients and warfarin reversal.
Key facts at a glance
- RxNorm
- 1670388
- Generic
- Profilnine
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention and treatment of bleeding episodes in patients with hemophilia B (Factor IX deficiency), rapid reversal of warfarin anticoagulation when bleeding is present or urgent surgery is required.
Contains human plasma-derived vitamin K-dependent clotting factors (primarily Factor IX, along with Factors II, VII, and X) that replace missing or deficient clotting factors, restoring the normal coagulation cascade to help form blood clots.
Administered via intravenous injection under physician supervision. Derived from human plasma with associated infection risk (though minimized through screening and processing). Monitor for signs of thromboembolic complications. Dosing individualized based on bleeding severity, patient weight, and desired Factor IX levels.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy