Moxidectin
Proheart is a brand-name heartworm preventive medication for dogs that provides protection against deadly heartworm disease caused by Dirofilaria immitis. The active ingredient moxidectin works by eliminating heartworm larvae before they can mature into adult worms, providing either monthly or extended protection depending on the formulation.
Proheart is a prescription heartworm preventive for dogs that kills heartworm larvae to prevent potentially fatal heartworm disease.
Key facts at a glance
- RxNorm
- 2178769
- Generic
- Proheart
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Proheart is indicated for the prevention of heartworm disease in dogs. It protects against infection by Dirofilaria immitis and may also help control certain other parasitic infections as determined by your veterinarian.
Moxidectin, the active ingredient, is an endectocide that acts on the nervous system of parasites, effectively killing heartworm larvae (microfilariae) before they can develop into adult worms. Different formulations provide protection lasting either one month or up to twelve months.
Proheart is a prescription medication for veterinary use only in dogs. Dogs must be tested for existing heartworm infection before starting treatment. Common side effects may include lethargy, vomiting, or injection site reactions. This medication should only be used under direct veterinary supervision and never administered to cats without specific veterinary guidance.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy