Moxidectin
Proheart 6 is a brand-name injectable heartworm preventive medication for dogs that provides protection against heartworm disease for a full 6 months with a single injection. The active ingredient moxidectin works by eliminating the immature form of heartworms (Dirofilaria immitis) transmitted by mosquitoes, helping to prevent canine heartworm disease. This prescription medication is administered by a veterinarian and is suitable for dogs of various ages when used according to label directions.
Proheart 6 is a 6-month injectable heartworm preventive for dogs containing moxidectin, administered by a veterinarian to prevent heartworm disease.
Key facts at a glance
- RxNorm
- 1551502
- Generic
- Proheart 6
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of heartworm disease (dirofilariasis) caused by Dirofilaria immitis in dogs. May also help prevent certain intestinal parasites including hookworm infections when used as part of a comprehensive parasite control program.
Contains moxidectin, a macrocyclic lactone that works by binding to glutamate-gated chloride channels in nerve and muscle cells of parasites, causing paralysis and death of heartworm larvae (microfilariae) before they can mature into adult worms.
Available by prescription only and must be administered by a licensed veterinarian. Not for use in cats or other animals. Dogs should be tested for existing heartworm infection before administration. Potential side effects may include injection site reactions, lethargy, or gastrointestinal upset. May interact with certain other medications; inform your veterinarian of all medications your pet is taking.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy