Dalteparin
Prolastin is a brand-name alpha-1 proteinase inhibitor (alpha-1 antitrypsin) replacement therapy. It is derived from human plasma and used to treat patients with alpha-1 antitrypsin deficiency, a genetic condition that can lead to emphysema and other lung diseases.
Prolastin is a plasma-derived protein therapy used to slow lung damage in patients with alpha-1 antitrypsin deficiency.
Key facts at a glance
- RxNorm
- 204213
- Generic
- Prolastin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prolastin is indicated for adults with alpha-1 antitrypsin deficiency who have established emphysema or other clinical manifestations of the condition. It is not used as a treatment for lung diseases caused by other factors such as smoking (though it may be used in smokers with confirmed AATD).
Alpha-1 antitrypsin is a naturally occurring protein that protects lung tissue from damage caused by enzymes like neutrophil elastase. In alpha-1 antitrypsin deficiency, insufficient levels of this protective protein lead to progressive lung destruction. Prolastin replaces the deficient AAT protein, helping to restore this protective barrier in the lungs.
Prolastin is administered intravenously by a healthcare professional. As it is derived from human plasma, there is a theoretical risk of transmitting infectious agents, though screening and purification processes minimize this risk. Patients should be monitored for potential hypersensitivity reactions. Treatment is typically long-term and does not cure the underlying deficiency. Specific dosing and frequency should be determined by the prescribing physician based on individual patient factors.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy