Propantheline
Propantheline is an anticholinergic medication that reduces excessive secretions and spasms by blocking acetylcholine action on muscarinic receptors throughout the body.
Propantheline is an anticholinergic used to reduce spasms and secretions in digestive and urinary tract conditions.
Key facts at a glance
- ATC
- A03AB05
- RxNorm
- 8761
- Generic
- Propantheline
- Class
- atc-a03
- Brands
- Probanthine
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Propantheline is used to treat peptic ulcer disease, irritable bowel syndrome, overactive bladder, urinary incontinence, and hyperhidrosis (excessive sweating). It helps manage conditions involving excessive secretions or smooth muscle spasms.
Propantheline blocks muscarinic acetylcholine receptors, preventing the neurotransmitter acetylcholine from binding. This reduces GI motility and secretions, decreases bladder muscle contractions, and reduces sweat gland activity.
This medication is contraindicated in patients with glaucoma, urinary retention, gastrointestinal obstruction, or myasthenia gravis. Common side effects include dry mouth, blurred vision, constipation, and tachycardia. Use with caution in elderly patients due to increased sensitivity to anticholinergic effects. Take 30 minutes before meals for best results.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy