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Methylene Blue

Published: August 9, 2026Updated: August 9, 2026

Provayblue is a brand-name medication containing methylene blue, primarily used to treat methemoglobinemia, a condition where hemoglobin cannot properly release oxygen to body tissues. It works by converting methemoglobin back to normal hemoglobin, restoring the blood's ability to transport oxygen.

Quick summary

Provayblue is a medication that treats methemoglobinemia by converting abnormal hemoglobin back to its normal form, restoring oxygen delivery in the blood.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 9, 2026Editorial policy

Key facts at a glance

RxNorm
1788985
Generic
Provayblue
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of methemoglobinemia (acquired and congenital), and used as a diagnostic dye for medical procedures. May be used in certain toxicology emergencies when indicated.

Acts as a reducing agent that converts methemoglobin to hemoglobin through a redox reaction, allowing the blood to resume normal oxygen-carrying and oxygen-delivering functions.

Should be administered under medical supervision. May cause discoloration of urine and skin (blue-green). Potential interactions with certain medications including serotonergic drugs. Contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Use during pregnancy only if clearly needed.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy