Ivosidenib
Pyrukynd (mitapivat) is a prescription medication used to treat hemolytic anemia in adults with pyruvate kinase (PK) deficiency. It works by activating the pyruvate kinase enzyme in red blood cells, which helps improve red blood cell survival and increase hemoglobin levels. This medication is specifically indicated for adults with this rare genetic blood disorder.
Pyrukynd is a pyruvate kinase activator used to treat hemolytic anemia in adults with PK deficiency by helping red blood cells function more effectively.
Key facts at a glance
- RxNorm
- 2594474
- Generic
- Pyrukynd
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Pyrukynd is indicated for the treatment of hemolytic anemia in adults with pyruvate kinase (PK) deficiency, a rare genetic disorder affecting red blood cells.
Mitapivat activates the pyruvate kinase enzyme in red blood cells, which helps improve red blood cell energy metabolism, increases red blood cell survival, and raises hemoglobin levels in affected patients.
Patients with iron overload requiring chelation therapy should not use Pyrukynd. It may cause fetal harm if used during pregnancy. Common side effects may include back pain, hypertension, and upper respiratory infections. Patients should have their hemoglobin and iron parameters monitored during treatment.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy