Prussian Blue
Radiogardase (Prussian blue) is a prescription medication used to treat internal contamination with radioactive cesium-137 or non-radioactive thallium. It works by binding to these radioactive or toxic substances in the gastrointestinal tract, preventing their absorption and facilitating their elimination from the body through feces. This medication is typically used following radiation emergencies or accidental exposure situations.
Radiogardase is an antidote for internal contamination with radioactive cesium or thallium that works by trapping these substances in the gut and promoting their excretion.
Key facts at a glance
- RxNorm
- 539398
- Generic
- Radiogardase
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of known or suspected internal contamination with radioactive cesium-137 or thallium. Used primarily in radiation emergency scenarios, nuclear accidents, or accidental exposure situations where these radioactive or toxic materials have been ingested or inhaled.
Radiogardase contains Prussian blue particles that have a crystalline structure capable of trapping and binding cesium and thallium ions through ion exchange. Once bound, the radioactive materials are trapped within the gut lumen and eliminated with feces, reducing internal radiation exposure and toxicity.
Most effective when given promptly after contamination. May cause constipation, dark stools, and electrolyte imbalances. Should be taken with food to reduce gastrointestinal irritation. Treatment duration varies based on contamination levels. Adequate hydration is important during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy