Raltegravir
Raltegravir is an HIV-1 integrase inhibitor used in combination with other antiretroviral medications for the treatment of HIV-1 infection in adults and pediatric patients. By blocking the integration of viral DNA into host cells, it helps prevent the virus from replicating and spreading.
Raltegravir is an HIV integrase inhibitor used as part of combination antiretroviral therapy to treat HIV-1 infection.
Key facts at a glance
- ATC
- J05AJ01
- RxNorm
- 719872
- Generic
- Raltegravir
- Class
- atc-j05
- Brands
- Isentress
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet, suspension
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of HIV-1 infection in combination with other antiretroviral agents, approved for use in adults and children weighing at least 2 kg.
Raltegravir inhibits HIV integrase, an enzyme essential for the integration of viral DNA into host cell chromosomes, thereby preventing viral replication.
Should be used as part of a combination regimen; may cause neuropsychiatric symptoms such as insomnia and depression; can be taken with or without food; tablet formulations include chewable and film-coated options.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy