Ramelteon
Ramelteon is a melatonin receptor agonist used to treat insomnia characterized by difficulty with sleep onset. It works by binding to melatonin MT1 and MT2 receptors in the brain, mimicking the natural sleep-wake cycle regulator. This medication is specifically indicated for adults struggling to fall asleep.
Ramelteon is a prescription sleep aid that works like melatonin to help initiate sleep for people with insomnia.
Key facts at a glance
- ATC
- N05CH02
- RxNorm
- 596205
- Generic
- Ramelteon
- Class
- atc-n05
- Brands
- Rozerem
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of insomnia characterized by difficulty with sleep onset in adults
Acts as a melatonin receptor agonist with high affinity for MT1 and MT2 receptors, promoting sleep by mimicking the activity of natural melatonin in the body
Should be taken within 30 minutes before bedtime, contraindicated in patients with severe hepatic impairment, and not recommended for use with strong CYP1A2 inhibitors. May cause drowsiness; patients should avoid driving or operating machinery until they know how the medication affects them.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy