Rasagiline
Rasagiline is a monoamine oxidase type B (MAO-B) inhibitor used to treat Parkinson's disease. It works by increasing dopamine levels in the brain, helping to improve motor symptoms such as tremor, stiffness, and slowness of movement. It can be used as monotherapy in early Parkinson's disease or as an adjunct to other Parkinson's medications in more advanced stages.
Rasagiline is a Parkinson's disease medication that increases brain dopamine levels by inhibiting the MAO-B enzyme.
Key facts at a glance
- ATC
- N04BD02
- RxNorm
- 134748
- Generic
- Rasagiline
- Class
- atc-n04
- Brands
- Azilect
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Rasagiline is used for the treatment of Parkinson's disease, both as initial monotherapy in early disease and as adjunctive therapy in more advanced stages alongside other antiparkinson medications.
Rasagiline is an irreversible inhibitor of monoamine oxidase type B (MAO-B), an enzyme that breaks down dopamine in the brain. By inhibiting MAO-B, it prevents the breakdown of dopamine, thereby increasing dopamine levels and improving dopaminergic neurotransmission.
Patients should avoid tyramine-rich foods (aged cheeses, cured meats, fermented products) due to risk of hypertensive crisis. Caution is needed when combining with other MAO inhibitors, antidepressants (especially SSRIs), or opioids due to risk of serotonin syndrome. Patients should inform their doctor of all medications before starting treatment.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy