Interferon Beta-1a
Rebif is a brand-name formulation of interferon beta-1a used to treat relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting MS, and active secondary progressive MS. As an immunomodulator, it helps reduce the frequency of MS relapses and may slow disease progression.
Rebif is an injectable interferon beta-1a medication used to treat relapsing forms of multiple sclerosis.
Key facts at a glance
- RxNorm
- 228271
- Generic
- Rebif
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting MS, and active secondary progressive MS in adults.
Rebif is an immunomodulator that works by binding to interferon receptors on cells, modulating immune response and reducing inflammation. It has antiviral properties and is thought to decrease the immune system's attack on the central nervous system.
Administered via subcutaneous injection, typically three times per week. Common side effects include flu-like symptoms (fever, chills, muscle aches), injection site reactions, and liver function abnormalities. Requires refrigeration and should not be used during pregnancy. Patients should be monitored for depression and suicidal ideation. May reduce blood counts and requires regular laboratory monitoring.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy