Rebyota
Rebyota is a microbiota-based treatment designed to prevent the recurrence of Clostridioides difficile (C. difficile) infection in adults. It is administered as a rectal enema following antibiotic treatment for recurrent C. diff infections. The medication works by introducing live bacterial spores to help restore healthy gut microbiome balance and reduce the risk of future infection episodes.
A rectal probiotic treatment used to prevent C. difficile infection from recurring after antibiotic therapy.
Key facts at a glance
- RxNorm
- 2626733
- Generic
- Rebyota
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of recurrent Clostridioides difficile (C. diff) infection in adults who have completed antibiotic treatment for a recurrent C. diff episode.
Contains live bacterial spores that help restore healthy gut microbiota balance, which may reduce C. diff recurrence by competitively inhibiting the bacteria.
Administered as a rectal enema by a healthcare professional. Should not be used in patients with known allergies to its components. Effectiveness and safety in immunocompromised patients may be different. Patients should inform their doctor of all medical conditions and medications before use.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy