Imipenem, Cilastatin, and Relebactam
Recarbrio is a combination antibiotic containing imipenem, cilastatin, and relebactam used to treat serious bacterial infections in adults. It is specifically indicated for complicated urinary tract infections and complicated intra-abdominal infections when caused by gram-negative bacteria resistant to other treatments.
Recarbrio is a broad-spectrum combination antibiotic for treating resistant gram-negative bacterial infections in hospitalized adults.
Key facts at a glance
- RxNorm
- 2184143
- Generic
- Recarbrio
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Recarbrio treats complicated urinary tract infections (cUTI) and complicated intra-abdominal infections (cIAI) in adults caused by susceptible gram-negative bacteria, including cases where other antibiotics may not be effective due to resistance.
Recarbrio combines three components: imipenem (a carbapenem antibiotic that inhibits bacterial cell wall synthesis), cilastatin (which prevents renal degradation of imipenem), and relebactam (which protects imipenem from certain bacterial resistance mechanisms by inhibiting beta-lactamases).
Recarbrio is administered intravenously and should only be used when clearly indicated to reduce the development of drug-resistant bacteria. It is contraindicated in patients with known hypersensitivity to carbapenems. Common side effects may include nausea, diarrhea, headache, and injection site reactions. Caution is needed in patients with renal impairment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy