Levoketoconazole
Recorlev is a cortisol synthesis inhibitor used to treat endogenous Cushing's syndrome in adult patients who are not candidates for surgery or for whom surgery has not been effective. It contains the active ingredient levoketoconazole and helps reduce cortisol levels in the body.
Recorlev is a prescription medication used to treat high cortisol levels in adults with Cushing's syndrome.
Key facts at a glance
- RxNorm
- 2588849
- Generic
- Recorlev
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Recorlev is indicated for the treatment of endogenous hypercortisolism (Cushing's syndrome) in adult patients with either persistent or recurrent disease who are not candidates for surgery or have not responded adequately to surgery.
Recorlev (levoketoconazole) inhibits enzymes involved in cortisol synthesis, primarily cytochrome P450 11B1 (CYP11B1), thereby reducing the production of cortisol by the adrenal glands.
Recorlev carries a boxed warning for hepatotoxicity and requires regular liver function monitoring. It should only be prescribed by healthcare providers experienced in treating Cushing's syndrome. Common side effects may include nausea, hypocortisolism, and fatigue. Patients should be monitored for signs of adrenal insufficiency during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy