Becaplermin
Regranex is a topical prescription medication containing becaplermin, a recombinant human platelet-derived growth factor. It is used to treat diabetic foot ulcers in patients whose wounds extend into the skin tissue. The medication is applied directly to the wound to help promote healing.
Regranex is a topical gel used to treat diabetic foot ulcers by applying growth factors directly to the wound to encourage healing.
Key facts at a glance
- RxNorm
- 219603
- Generic
- Regranex
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Regranex is indicated for the treatment of lower extremity diabetic neuropathic ulcers that extend into the subcutaneous tissue or beyond, when used as part of a comprehensive wound care program including debridement, pressure relief, and infection control.
The active ingredient becaplermin is a recombinant human platelet-derived growth factor (PDGF) that stimulates granulation tissue formation and promotes wound healing by encouraging cell proliferation and migration at the ulcer site.
Regranex should be applied once daily in a thin layer to the wound surface. It is contraindicated in patients with known hypersensitivity to becaplermin or any component of the product. The safety and effectiveness in patients with wounds that extend to muscle, tendon, or bone has not been established. Common side effects may include local skin reactions at the application site.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy