Sodium Phenylbutyrate
Relyvrio is a prescription medication combining sodium phenylbutyrate and taurursodiol, approved for the treatment of amyotrophic lateral sclerosis (ALS) in adults. The exact mechanism is not fully understood but may involve reducing cellular stress and improving mitochondrial function. Clinical trials demonstrated that Relyvrio may slow functional decline in patients with ALS.
Relyvrio is an FDA-approved oral combination medication for adults with ALS that may help slow disease progression.
Key facts at a glance
- RxNorm
- 2613969
- Generic
- Relyvrio
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Relyvrio is indicated for the treatment of amyotrophic lateral sclerosis (ALS) in adults. It is not a cure for ALS but may help slow the progression of functional decline associated with the disease.
The exact mechanism of action has not been fully established. Sodium phenylbutyrate is believed to help reduce cellular stress and protein aggregation, while taurursodiol may support mitochondrial function and help protect nerve cells from damage. Together, these components may help preserve neuronal health.
Relyvrio is taken orally as a suspension. Common side effects may include diarrhea, abdominal pain, nausea, and upper respiratory infections. Patients should inform their healthcare provider about any liver conditions, as monitoring may be recommended. The medication should be used as prescribed and patients should discuss all current medications with their doctor before starting treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy