Sevelamer
Renagel (sevelamer hydrochloride) is a phosphate binder medication used to control high phosphorus levels in the blood of patients with chronic kidney disease who are on dialysis. It works by binding to dietary phosphate in the intestines, preventing its absorption into the bloodstream. This medication is typically used when diet alone and other treatments are insufficient to manage hyperphosphatemia.
Renagel is a phosphate binder used to control high phosphorus levels in dialysis patients with chronic kidney disease.
Key facts at a glance
- RxNorm
- 135118
- Generic
- Renagel
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Renagel is indicated for the control of serum phosphorus in patients with end-stage renal disease (ESRD) on dialysis (hemodialysis or peritoneal dialysis) who have hyperphosphatemia. It is used when phosphorus levels cannot be adequately controlled by dietary phosphate restriction alone.
Renagel is a non-absorbed phosphate binding polymer that works in the gastrointestinal tract. It binds to dietary phosphate from food, forming a complex that is excreted in feces, thereby preventing phosphate absorption into the bloodstream and helping to lower serum phosphorus levels.
Renagel should be taken with meals as directed. Patients should inform their healthcare provider of all medications being taken, as it may affect absorption of other drugs. Common side effects may include gastrointestinal symptoms such as nausea, vomiting, or constipation. Regular monitoring of serum phosphorus and other electrolytes is important during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy