Retapamulin
Retapamulin is a topical antibiotic medication used to treat certain bacterial skin infections, most commonly impetigo. It belongs to the pleuromutilin class of antibiotics and is applied directly to the skin.
Topical antibiotic for treating minor skin infections like impetigo.
Key facts at a glance
- ATC
- D06AX13
- RxNorm
- 642274
- Generic
- Retapamulin
- Class
- atc-d06
- Brands
- Altabax
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- ointment
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Retapamulin is primarily used to treat impetigo, a contagious bacterial skin infection characterized by red sores or blisters. It may also be prescribed for other minor skin infections caused by susceptible bacteria such as Staphylococcus aureus and Streptococcus pyogenes.
Retapamulin is a pleuromutilin antibiotic that works by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit of bacteria, preventing the formation of essential proteins needed for bacterial growth and survival.
Retapamulin is for topical use only and should not be applied to the eyes, mouth, or nose. Patients should wash their hands before and after application. While generally well-tolerated, some individuals may experience local skin reactions. Complete the full course of treatment as prescribed by a healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy