Tretinoin
Retin-A (tretinoin) is a topical retinoid used primarily to treat acne by promoting skin cell turnover and preventing clogged pores. It is also prescribed for reducing fine lines, wrinkles, and hyperpigmentation, making it popular in both medical and cosmetic dermatology.
Retin-A is a topical acne treatment that also addresses signs of aging by accelerating skin cell renewal.
Key facts at a glance
- RxNorm
- 153101
- Generic
- Retin-A
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Retin-A is indicated for the treatment of acne vulgaris, including comedonal acne (blackheads and whiteheads) and inflammatory acne. It is also used off-label to improve skin texture, reduce fine wrinkles, address hyperpigmentation, and improve overall skin appearance.
Retin-A works by binding to retinoic acid receptors in skin cells, promoting rapid cell turnover and shedding of dead skin cells. This prevents pores from becoming clogged, reduces the formation of comedones, and stimulates collagen production in the dermis.
Retin-A increases sun sensitivity, so daily sunscreen use is essential. Skin irritation, redness, and peeling may occur initially and typically subside with continued use. It should not be used during pregnancy. Avoid applying to sensitive areas like eyes, mouth, and broken skin.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy