Luspatercept
Rezlidhia is a prescription brand-name medication used to treat adults with relapsed or refractory acute myeloid leukemia (AML) that has a specific genetic mutation called IDH1. It is an oral medication that works by inhibiting the mutated IDH1 enzyme to help promote normal blood cell development.
Rezlidhia is an oral targeted therapy for adults with relapsed/refractory IDH1-mutant AML.
Key facts at a glance
- RxNorm
- 2623649
- Generic
- Rezlidhia
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of adults with relapsed or refractory acute myeloid leukemia (AML) that has an isocitrate dehydrogenase-1 (IDH1) mutation, as detected by an FDA-approved test.
Olutasidenib is an IDH1 inhibitor that works by blocking the activity of mutated IDH1 enzyme, which helps abnormal blood-forming cells differentiate into normal, healthy blood cells.
Rezlidhia may cause differentiation syndrome, a serious condition that can be fatal if not treated. Patients should be monitored for symptoms such as fever, difficulty breathing, rapid weight gain, and swelling. Common side effects may include nausea, fatigue, joint pain, and elevated liver enzymes. Drug interactions and pregnancy precautions apply.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy