Oxymetazoline
Rhofade is a topical prescription medication containing oxymetazoline that is applied directly to the facial skin. It is specifically approved to treat persistent facial erythema (redness) associated with rosacea in adults. The medication works by constricting blood vessels in the skin to reduce visible redness, providing relief for individuals who experience chronic facial flushing.
Rhofade is a topical cream that reduces facial redness associated with rosacea by constricting blood vessels in the skin.
Key facts at a glance
- RxNorm
- 1869817
- Generic
- Rhofade
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Rhofade is used to treat persistent facial erythema (redness) associated with rosacea in adults. It is not a cure for rosacea but helps manage the cosmetic symptom of persistent facial redness.
Rhofade contains oxymetazoline, an alpha-adrenergic agonist. When applied topically, it causes vasoconstriction (narrowing) of the blood vessels in the facial skin, which reduces blood flow to the surface and decreases visible redness.
Rhofade is for topical use only on the face and should not be used in the eyes, mouth, or vagina. Common side effects may include application site reactions such as redness, itching, or burning. Patients with certain cardiovascular conditions, narrow-angle glaucoma, or who are taking certain medications should discuss use with their healthcare provider. Effects typically begin within hours of application.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy