Rifamycin Sv
Rifamycin SV is a rifamycin-class antibiotic used to treat infectious diarrhea and traveler's diarrhea caused by susceptible non-invasive strains of E. coli, and to reduce the risk of hepatic encephalopathy.
Rifamycin SV is an intestinal antibiotic primarily used for traveler's diarrhea and reducing hepatic encephalopathy risk.
Key facts at a glance
- ATC
- A07AA13
- RxNorm
- 35616
- Generic
- Rifamycin Sv
- Class
- atc-a07
- Brands
- Aemcolo
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of acute, non-invasive traveler's diarrhea caused by susceptible strains of Escherichia coli in adults and children 12 years and older. Also used as an adjuvant therapy for reducing risk of overt hepatic encephalopathy recurrence in adults with liver cirrhosis.
Rifamycin SV is a bactericidal antibiotic that inhibits bacterial DNA-dependent RNA polymerase, preventing bacterial protein synthesis. It has a broad spectrum of activity against gram-positive and gram-negative bacteria, though oral administration results in minimal systemic absorption, allowing for localized action in the gastrointestinal tract.
Common side effects include headache, abdominal pain, and constipation. May cause harmless red-orange discoloration of feces, urine, saliva, sweat, and tears. Not recommended for patients with known hypersensitivity to rifamycin-class antibiotics. Should not be used for diarrhea complicated by fever or bloody stools. Effectiveness in treating traveler's diarrhea caused by pathogens other than E. coli has not been established.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy