Riluzole
Rilutek (riluzole) is a prescription medication used to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It works by reducing glutamate activity in the brain, which may help slow the progression of the disease and extend survival in some patients. This medication is not a cure for ALS but is used as part of a comprehensive treatment approach.
Rilutek is a medication used to treat ALS by reducing glutamate activity to help slow disease progression.
Key facts at a glance
- RxNorm
- 196501
- Generic
- Rilutek
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Rilutek is indicated for the treatment of amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to muscle weakness and eventual loss of muscle function.
While the exact mechanism is not fully understood, Rilutek is believed to work by decreasing glutamate activity in the brain. Excessive glutamate is thought to contribute to nerve cell damage in ALS, and by reducing glutamate levels, the medication may help protect remaining nerve cells from further damage.
Rilutek should be taken exactly as prescribed, typically on an empty stomach. Common side effects may include dizziness, gastrointestinal symptoms, and changes in liver function tests. Regular monitoring of liver function is typically recommended during treatment. Patients should inform their healthcare provider of all medications and health conditions before starting therapy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy