Valoctocogene Roxaparvovec
Roctavian is a gene therapy medication for adults with severe hemophilia A. It works by delivering a functional copy of the factor VIII gene to help the body produce its own clotting factor, potentially reducing or eliminating the need for regular factor VIII replacement therapy.
Roctavian is a one-time gene therapy for adults with severe hemophilia A that enables the body to produce its own clotting factor VIII.
Key facts at a glance
- RxNorm
- 2641616
- Generic
- Roctavian
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of severe hemophilia A in adults without pre-existing antibodies to adeno-associated virus serotype 5 (AAV5)
Delivers a functional copy of the factor VIII gene via an AAV5 vector into liver cells, allowing the body to produce its own clotting factor
Administered as a single intravenous infusion; requires regular liver enzyme monitoring; not for patients with pre-existing AAV5 antibodies; clinical trial follow-up continues to assess long-term durability
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy