Eflapegrastim
Rolvedon is a prescription medication used to reduce the risk of infection in patients with non-myeloid cancers undergoing myelosuppressive chemotherapy. It belongs to a class of drugs called granulocyte colony-stimulating factors (G-CSFs) that work by stimulating the bone marrow to produce more white blood cells, specifically neutrophils, which are essential for fighting infections.
Rolvedon helps prevent infections in cancer patients receiving chemotherapy by boosting white blood cell production.
Key facts at a glance
- RxNorm
- 2612543
- Generic
- Rolvedon
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Rolvedon is indicated to reduce the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia.
Rolvedon is a long-acting granulocyte colony-stimulating factor (G-CSF) that binds to specific cell surface receptors on neutrophil progenitor cells, stimulating their proliferation, differentiation, and activation. This increases the production and release of neutrophils from the bone marrow into the bloodstream.
Rolvedon is administered as a subcutaneous injection. It should not be used in patients with known hypersensitivity to the drug or its components. Patients should be monitored for signs of allergic reactions, splenic rupture, and acute respiratory distress syndrome. The medication is typically given at least 24 hours after chemotherapy and not within 14 days before the next chemotherapy dose.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy