Rosuvastatin and Ezetimibe
Roszet is a brand-name combination medication containing ezetimibe and rosuvastatin, used to treat high cholesterol in patients who need additional lipid-lowering therapy beyond diet and statin therapy alone. The two active ingredients work through different mechanisms to reduce LDL cholesterol levels.
Roszet is a cholesterol-lowering medication combining two drugs that reduce cholesterol through different pathways.
Key facts at a glance
- RxNorm
- 2536055
- Generic
- Roszet
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Roszet is indicated as an adjunct to diet for the treatment of primary hyperlipidemia (heterozygous familial and nonfamilial) and mixed dyslipidemia, to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B, and non-HDL cholesterol levels.
Roszet contains two cholesterol-lowering agents: rosuvastatin, a statin that inhibits HMG-CoA reductase in the liver to reduce cholesterol synthesis, and ezetimibe, which blocks cholesterol absorption in the small intestine. Together they provide complementary cholesterol reduction.
Common side effects include muscle pain, headache, and joint pain. As with all statins, there is a risk of liver enzyme elevation and rare muscle-related complications. It should not be used during pregnancy or breastfeeding. Patients should be advised to report unexplained muscle pain, tenderness, or weakness.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy