Rucaparib
Rubraca is a prescription medication used to treat certain types of ovarian, fallopian tube, and primary peritoneal cancer. It is specifically indicated for patients with deleterious BRCA mutations who have received prior chemotherapy treatment.
Rubraca is a PARP inhibitor used to treat BRCA-mutated ovarian cancers.
Key facts at a glance
- RxNorm
- 1862585
- Generic
- Rubraca
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Rubraca is indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy, as well as for the treatment of patients with deleterious BRCA mutations who have received two or more prior chemotherapies.
Rubraca is a poly (ADP-ribose) polymerase (PARP) inhibitor. It works by blocking the PARP enzyme, which is involved in repairing damaged DNA in cells. In cancer cells with BRCA mutations (which impair DNA repair), blocking PARP leads to accumulation of DNA damage, causing the cancer cells to die.
Common side effects include fatigue, nausea, abdominal pain, and changes in blood cell counts. Regular monitoring of blood counts is recommended during treatment. Rubraca may cause serious risks including bone marrow problems and should not be used during pregnancy due to potential harm to an unborn baby. Patients should discuss complete medical history and all current medications with their healthcare provider before starting treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy