Rituximab
Ruxience is a biosimilar medication that references Rituxan (rituximab). It is a monoclonal antibody that targets CD20, a protein found on the surface of B cells, leading to the destruction of these cells. This medication is used to treat certain autoimmune disorders and cancers involving B cells.
Ruxience is a biosimilar monoclonal antibody used to treat B-cell cancers and autoimmune conditions by targeting and destroying CD20-expressing B cells.
Key facts at a glance
- RxNorm
- 2273513
- Generic
- Ruxience
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Ruxience is used to treat non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris.
Ruxience is a monoclonal antibody that binds to the CD20 antigen on the surface of B cells, triggering immune-mediated destruction of these cells.
As a biosimilar, Ruxience is highly similar to Rituxan with no clinically meaningful differences. It carries risks of infusion reactions, infections, and potential reactivation of hepatitis B. Patients should be monitored closely during and after infusion. Live vaccines should be avoided during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy