Olopatadine and Mometasone
Ryaltris is a prescription nasal spray combining an antihistamine (olopatadine) and a corticosteroid (mometasone) to treat seasonal allergic rhinitis symptoms such as nasal congestion, sneezing, runny nose, and itchy nose in patients 12 years and older. The dual-action formula works by blocking histamine and reducing inflammation in the nasal passages.
Ryaltris is a prescription nasal spray for seasonal allergies that combines an antihistamine and corticosteroid to relieve nasal allergy symptoms.
Key facts at a glance
- RxNorm
- 2591807
- Generic
- Ryaltris
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of symptoms associated with seasonal allergic rhinitis (hay fever), including nasal congestion, sneezing, rhinorrhea (runny nose), and nasal itching in patients 12 years of age and older.
Ryaltris combines two active ingredients: olopatadine hydrochloride (an antihistamine/H1 receptor antagonist) that blocks histamine to reduce allergic symptoms, and mometasone furoate (a corticosteroid) that reduces inflammation and swelling in the nasal passages.
For intranasal use only. Common side effects may include epistaxis (nosebleeds), nasal discomfort, and headache. Should be used as directed by a healthcare provider. Avoid contact with eyes. Not recommended for use in pediatric patients under 12 years without medical advice.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy