Sacrosidase
Sacrosidase is an oral enzyme replacement therapy containing the digestive enzyme sucrase, specifically indicated for the treatment of congenital sucrase-isomaltase deficiency (CSID). This rare genetic disorder impairs the body's ability to break down sucrose (table sugar) and isomaltose, leading to digestive symptoms. The medication helps patients digest sucrose-containing foods, reducing symptoms such as chronic diarrhea, abdominal pain, and bloating.
Sacrosidase is an enzyme replacement therapy that compensates for missing digestive enzymes in patients with congenital sucrase-isomaltase deficiency, allowing them to digest sucrose.
Key facts at a glance
- ATC
- A16AB06
- RxNorm
- 214817
- Generic
- Sacrosidase
- Class
- atc-a16
- Brands
- Sucraid
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Congenital sucrase-isomaltase deficiency (CSID), a rare genetic disorder in which patients lack the enzymes sucrase and isomaltase needed to break down sucrose and isomaltose, resulting in inability to digest sugar and certain starches.
Sacrosidase provides exogenous sucrase enzyme that hydrolyzes (splits) sucrose into glucose and fructose in the intestinal lumen, enabling proper absorption of these sugars that would otherwise pass undigested and cause osmotic diarrhea.
Should be taken orally with each meal or snack; store at room temperature and use within 30 days of opening; should not be mixed with hot liquids as heat can inactivate the enzyme; patients should continue following a sucrose-restricted diet as directed by their healthcare provider; efficacy and safety have been established primarily in pediatric and adult patients with confirmed CSID.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy