Cyclosporine
Sandimmune (cyclosporine) is a calcineurin inhibitor immunosuppressant that reduces the activity of the immune system. It is primarily used to prevent organ rejection in transplant patients and to treat certain autoimmune conditions when other treatments have not been effective.
Sandimmune is an immunosuppressant used to prevent organ rejection and treat autoimmune conditions by reducing immune system activity.
Key facts at a glance
- RxNorm
- 202816
- Generic
- Sandimmune
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevents rejection of kidney, liver, and heart transplants; treats severe autoimmune conditions including rheumatoid arthritis, psoriasis, and atopic dermatitis when conventional therapies are inadequate.
Inhibits calcineurin, a key enzyme in T-cell activation, thereby suppressing the immune response that would otherwise attack transplanted organs or cause autoimmune inflammation.
Requires regular blood level monitoring due to narrow therapeutic window; may cause kidney toxicity, hypertension, and increased infection risk; multiple drug interactions exist; generic substitution should only be made with careful medical supervision.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy